DAMS CRS-Paraclinicals Pathology 2020 by Faculty DAMS
Author:Faculty, DAMS [Faculty, DAMS]
Language: eng
Format: epub
Publisher: DAMS
Published: 2020-03-07T16:00:00+00:00
the most common hepatotoxin causing acute liver failure is acetaminophen.
the most common hepatotoxin causing chronic liver disease is alcohol.
Unpredictable / Idiosyncratic e.g. Chlorpromazine, sulfonamides, methyldopa, allopurinol.
Alcoholic Liver Disease:
Hepatic Steatosis.
Alcoholic hepatitis.
Cirrhosis.
Steatosis Micro vesicular → Macro vesicular
Initially Centrilobular.
Liver: Enlarged, yellow, greasy. Easily fractured.
Reversible- till fibrosis appears.
Hepatitis:
Hepatocyte swelling and necrosis.
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